Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF4A All Species: 27.88
Human Site: S407 Identified Species: 40.89
UniProt: O95239 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95239 NP_036442.3 1232 139881 S407 E K L S R G L S E A A G Q T A
Chimpanzee Pan troglodytes XP_518055 1227 139177 S407 E K L S R C L S E A A G Q T A
Rhesus Macaque Macaca mulatta XP_001084213 1234 139742 S407 E K L S R G L S E A A G Q T A
Dog Lupus familis XP_549061 1234 139874 S408 E K L S R G L S E A A G Q T A
Cat Felis silvestris
Mouse Mus musculus P33174 1231 139533 S408 E K L S R G L S E A A G Q T A
Rat Rattus norvegicus Q7M6Z5 1394 158861 E416 L G Y Q D C I E Q A F A F L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 S410 E K L S R G L S E A A G Q T A
Frog Xenopus laevis Q91784 1226 138905 G408 G K L S R E L G E A A V Q T A
Zebra Danio Brachydanio rerio Q58G59 1363 154819 E466 S G L D S G I E S S S T E D S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 T110 F A Y G Q T G T G K T F T M E
Honey Bee Apis mellifera XP_395595 1064 123475 T389 Q K K I R D L T E K L N S N L
Nematode Worm Caenorhab. elegans P46873 699 78760 L25 E K D L N T T L C V G M T P N
Sea Urchin Strong. purpuratus P46872 699 78679 T25 R P L N S K E T G Q G F K S V
Poplar Tree Populus trichocarpa XP_002302432 1055 118553 M358 G G N S R T V M I A C I S P A
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_199593 1035 116715 T357 A D I N A E E T L N T L K Y A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 E254 A S G Q T L E E A K K I N K S
Conservation
Percent
Protein Identity: 100 93.1 96.4 94.8 N.A. 87 27 N.A. N.A. 74.5 68.5 25.8 N.A. 26.9 36.8 27.1 27.3
Protein Similarity: 100 95.6 97.2 97 N.A. 92.7 47.6 N.A. N.A. 85.9 82.1 45.1 N.A. 41.4 56.3 38.4 39.3
P-Site Identity: 100 93.3 100 100 N.A. 100 6.6 N.A. N.A. 100 73.3 13.3 N.A. 0 26.6 13.3 6.6
P-Site Similarity: 100 93.3 100 100 N.A. 100 20 N.A. N.A. 100 73.3 46.6 N.A. 13.3 40 13.3 33.3
Percent
Protein Identity: 33.2 N.A. N.A. 32.7 N.A. 26.7
Protein Similarity: 51 N.A. N.A. 51 N.A. 44.5
P-Site Identity: 26.6 N.A. N.A. 6.6 N.A. 0
P-Site Similarity: 33.3 N.A. N.A. 33.3 N.A. 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 7 0 0 7 0 0 0 7 57 44 7 0 0 57 % A
% Cys: 0 0 0 0 0 13 0 0 7 0 7 0 0 0 0 % C
% Asp: 0 7 7 7 7 7 0 0 0 0 0 0 0 7 0 % D
% Glu: 44 0 0 0 0 13 19 19 50 0 0 0 7 0 7 % E
% Phe: 7 0 0 0 0 0 0 0 0 0 7 13 7 0 0 % F
% Gly: 13 19 7 7 0 38 7 7 13 0 13 38 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 7 7 0 0 13 0 7 0 0 13 0 0 0 % I
% Lys: 0 57 7 0 0 7 0 0 0 19 7 0 13 7 0 % K
% Leu: 7 0 57 7 0 7 50 7 7 0 7 7 0 7 7 % L
% Met: 0 0 0 0 0 0 0 7 0 0 0 7 0 7 0 % M
% Asn: 0 0 7 13 7 0 0 0 0 7 0 7 7 7 7 % N
% Pro: 0 7 0 0 0 0 0 0 0 0 0 0 0 13 0 % P
% Gln: 7 0 0 13 7 0 0 0 7 7 0 0 44 0 0 % Q
% Arg: 7 0 0 0 57 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 7 7 0 50 13 0 0 38 7 7 7 0 13 7 13 % S
% Thr: 0 0 0 0 7 19 7 25 0 0 13 7 13 44 0 % T
% Val: 0 0 0 0 0 0 7 0 0 7 0 7 0 0 13 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 13 0 0 0 0 0 0 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _